Julio Cordero
Postdoctoral Fellow
Julio.Cordero@ucsf.edu


Education/Research
2009 - current Postdoc, Department of Physiology, UCSF; Advisor: Prof. David J. Julius
2008-2009 Postdoctoral Fellow, Department of Biochemistry and Molecular Biology, University of Chicago, USA.
2008 PhD., University of Virginia, USA
2001 Licenciate in Biology. Universidad Central de Venezuela, Facultad de Ciencias, Biology School, 2001. Venezuela

Publications


Raghuraman H, Cordero-Morales JF, Jogini V, Pan AC, Kollewe A, Roux B and Perozo P. Mechanism of Cd2+-coordination during slow inactivation in potassium channels. Structure 2012: (accepted)

Cordero-Morales JF*, Gracheva EO* and Julius D. Cytoplasmic Ankyrin Repeat Domains of TRPA1 Dictate Sensitivity to Thermal and Chemical Stimuli. Proc Natl Acad Sci 2011, 108:E1184–E1191.

Ferrer-Villada T, Cordero-Morales JF, Arias M, Ficker E, Medovoy D, Perozo E and Tristani-Firouzi M. Molecular coupling in the hERG K+ channel inactivation pathway. J Biol Chem 2011, 286:39091-9.

Gracheva EO*, Julio F. Cordero-Morales*, José A. González-Carcacía, Nicholas T. Ingolia, Carla I. Aranguren, Carlo Manno, Jonathan S. Weissman and David Julius. Ganglion-specific splicing of TRPV1 underlies infrared sensation in vampire bats. Nature 2011: 476(7358):88-91

Cordero-Morales JF, Jogini V, Chakrapani S, and Perozo E. (2011) A multipoint hydrogen bond network underlying KcsA C-type inactivation. Biophysical Journal, 100:2387-2393.

Chakrapani S*, Cordero-Morales JF*, Jogini V, Pan A, Cortes DM, Roux B and Perozo, E. (2011) On the structural basis of modal gating behavior in K+ channels. Nature Structural and Molecular Biology, 18:67-75.

Cuello LG, Jogini V, Cortes DM, Pan AC, Gagnon DH, Dalmas O, Cordero-Morales JF, Chakrapani S, Roux B and Perozo E. (2010) Structural Basis for the Coupling between Activation and Inactivation Gate in Potassium Channels. Nature, 466:272-275.

Elena O. Gracheva, Nicolas T. Ingolia, Yvonne M. Kelly, Julio F. Cordero-Morales, Gunther Hollopeter, Alexander T. Chesler, Elda E. Sánchez, John C. Perez, Jonathan S. Weissman, and David Julius (2010) Molecular Basis of Infrared Detection by Snakes. Nature 464(7291): 1006–1011.

Chakrapani S*, Cordero-Morales JF*, Jogini V, Pan A, Cortes DM, Roux B and Perozo, E. On the structural basis of modal gating behavior in K+ channels. Nature Structural and Molecular Biology. (Accepted) * These authors equally contributed to this work.

Cuello LG, Jogini V, Cortes DM, Pan AC, Gagnon DH, Dalmas O, Cordero-Morales JF, Chakrapani S, Roux B and Perozo E. 2010. Structural Basis for the Coupling between Activation and Inactivation Gate in Potassium Channels. Nature, 466:272-276.

Gracheva EO, Ingolia NT, Kelly YM, Cordero-Morales JF, Hollopeter G, Chesler AT, Sánchez EE, Perez JC, Weissman JS, and Julius D. 2010. Molecular Basis of Infrared Detection by Snakes. Nature, 464:1006-1011.

Vásquez V., Sotomayor M., Cordero-Morales J.F., Schulten K., and Perozo E. (2008). A Structural Mechanism for MscS gating in Lipid Bilayers. Science, 321:1210- 1214.

Cordero-Morales J.F., Jogini V., Lewis A., Vásquez V., Cortes D.M, Roux B., and Perozo E. (2007). Molecular driving forces determining potassium channel slow inactivation. Nature Structural and Molecular Biology, 14(11): 1062-1069.

Chakrapani S., Cordero-Morales J.F., and Perozo E. (2007). A quantitative description of KcsA gating. Macroscopic current I. Journal of General Physiology 130: 465-478.

Chakrapani S., Cordero-Morales J.F., and Perozo E. (2007). A quantitative description of KcsA gating. Single channel current II. Journal of General Physiology 130: 479-496.

Cordero-Morales J.F., Cuello L., Zhao Y., Jogini V., Cortes D.M., Roux B., and Perozo E. (2006). Molecular determinants of gating at the potassium channel selectivity filter. Nature Structural and Molecular Biology 13(4):311-318. (Journal Cover).

Cordero-Morales J.F., Cuello L., and Perozo E. (2006). Voltage-dependent gating at the potassium channel selectivity filter. Nature Structural and Molecular Biology 13(4):319-321.

Blunck R., Cordero-Morales J.F., Cuello L., Perozo E., and Bezanilla F. (2006). Detection of the opening of the bundle crossing in KcsA with fluorescence lifetime spectroscopy reveals the existence of two gates for ion conduction. Journal of General Physiology. 128(5):569-581.

Cordero J.F., Rodriguez P., Romero P.(2004). Differences in intramembrane particles distribution in young and old human erythrocytes. Cell Biol Int 28(6):423-31. 9) Cordero J.F., Romero P. (2002). Caffeine activates mechanosensitive Ca2+ channels in human red cells. Cell Calcium 31(5), 189-200




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