Elena Gracheva
Postdoctoral Fellow
Elena.Gracheva@ucsf.edu


Education/Research
2008 - current Postdoc, Department of Physiology, UCSF; Advisor: Prof. David J. Julius
2002-2006 Ph.D., University of Illinois (UIC), Chicago, USA
1996-2001 M.S., Biological Sciences Biochemistry
Moscow State University (MSU), Moscow, Russia

Publications

Cordero-Morales, JF, Gracheva, EO and Julius D Cytoplasmic ankyrin repeats of TRPA1 dictate sensitivity to thermal and chemical stimuli. Proc Natl Acad Sci, 2011 Sept. 19 (PMC Journal – In Process)

Gracheva EO*, Julio F. Cordero-Morales*, José A. González-Carcacía, Nicholas T. Ingolia, Carla I. Aranguren, Carlo Manno, Jonathan S. Weissman and David Julius. Ganglion-specific splicing of TRPV1 underlies infrared sensation in vampire bats. Nature 2011: 476(7358):88-91

Gracheva EO*, Ingolia NT*, Kelly YM, Cordero-Morales JF, Hollopeter G, Chesler AT, Sánchez EE, Perez JC, Weissman JS, Julius D. Molecular basis of infrared detection by snakes. Nature. 2010;464(7291):1006-11

Gracheva EO, Gayla Hadwiger, Michael L, Richmond JE. Direct interactions between C. Elegans RAB-3 and RIM provide a functionally significant to target vesicles to presynaptic density. Neurosci Letters. 2008, 444(2):137-42

Silva R.A.G.D, Huang R, Morris J, Fang J, Gracheva EO, Ren G, Kontush A, Jerome WG, Rye KA, Davidson WS. The structure of Apolipoprotein A-I in spherical high density lipoproteins of different size. PNAS. 2008, 105(34):12176-81

Bagriantsev S, Gracheva EO, Richmond JE, and Liebman SW. Variant-specific [PSI+] infection is transmitted by Sup35 polymers within [PSI+] aggregates with heterologous protein composition. Mol Biol Cell. 2008, 19(6):2433-43.

Wang W, Bouhours M, Gracheva EO, Liao EH, Xu K, Sengar AS, Xin X, Roder J, Boone C, Richmond JE, Zhen M, Egan SE. ITSN-1 controls vesicle recycling at the neuromuscular junction and functions in parallel with DAB-1.Traffic. 2008, 9(5):742-54.

Gracheva EO, Burdina AO, Touroutine D, Richmond JE. Tomosyn negatively regulates CAPS-dependent peptide release at Caenorhabditis elegans synapses. J Neurosci. 2007, 27(38):10176-10184

Gracheva EO, Burdina AO, Touroutine D, Berthelot-Grosjean M, Parekh H, Richmond JE. Tomosyn negatively regulates both synaptic transmitter and neuropeptide release at the C. elegans neuromuscular junction. J Physiol. 2007, 585(Pt 3): 705-9.

Gracheva EO*, Vitrenko YA*, Richmond JE, Liebman SW. Visualization of aggregation of the Rnq1 prion domain and cross-seeding interactions with Sup35NM. J Biol Chem. 2007, 282(3): 1779-87.

Gracheva EO, Burdina AO, Holgado AM, Berthelot-Grosjean M, Hadwiger G, Nonet ML, Weimer RM, Richmond JE. Tomosyn inhibits Synaptic Vesicle Priming in Caenorhabditis elegans. PLoS Biology. 2006, 4(8).

Weimer RM*, Gracheva EO*, Meyrignac O, Miller KG, Richmond JE, Bessereau J. UNC-13 and UNC-10/Rim Localize Synaptic Vesicles to Specific Membrane Domains. J Neurosci. 2006, 26(31): 8048-7.

Wang Y, Gracheva EO, Richmond JE, Kawano T, Couto JM, Calarco J, Vijayarantamn V, Jin Y, and Zhen M. A Novel C2H2 Zinc-finger Protein SYD-9 Regulates Synaptic Transmission. Proc Natl Acad Sci USA. 2006, 103(27): 10450-5.

Goncharova EA, Vorotnikov AV, Gracheva EO, Wang CL, Panetteri JR, Stepanova VV, Tkachuk VA. Activation of p38 MAP-kinase and caldesmon phosphorylation are essential for urokinase-induced human smooth muscle cell migration. Biol Chem. 2002, 383(1): 115-26.




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