Publications
Research Articles
1. Rubenstein, J.L.R., Brutlag, D. and Clayton, D.A. The mitochondrial DNA of Drosophila melanogaster exists in two distinct and stable superhelical forms. Cell 12: 471-482, 1977.
2. Hruska, J.F., Clayton, D.A., Rubenstein, J.L.R., and Robinson, W. S. Structure of the hepatitis B Dane particle before and after the Dane particle DNA polymerase reaction. J. Virology. 21: 666-672, 1977.
3. Battey, J., Rubenstein, J.L.R., and Clayton, D.A. Transcription pattern of Drosophila melanogaster mitochondrial DNA. In: Extrachromosomal DNA, Borst, P., Cummings, D., Dawid, I.D. and Weissman, S. Eds. Academic Press, 427-442, 1979.
4. Rubenstein, J.L.R., Smith, B.A., and McConnell, H.M., Lateral diffusion in binary mixtures of cholesterol and phosphatidylcholines. Proc. Natl. Acad. Sci. USA 76: 15-18, 1979.
5. Rubenstein, J.L.R., Owicki, J.C. and McConnell, H. M. A spin label study of motions in binary mixtures of cholesterol and phosphatidylcholines Biochemistry 19: 569-573, 1980.
6. Smith, L.M., Rubenstein, J.L.R., Parce, J.W. and McConnell, H.M. Lateral diffusion of M-13 coat protein in binary mixtures of cholesterol and phosphatidylcholines Biochemistry 19: 5907-5911, 1980.
7. Rubenstein, J.L.R., Fine, R.E., Luskey, B.D., and Rothman, J.E. Purification of coated vesicles by agarose gel electrophoresis. J. Cell Biology 89: 357-361, 1981.
8. Rubenstein, J.L.R., and Chappell, T.G. Construction of a synthetic messenger RNA encoding a membrane protein. J. Cell Biology 96: 1464-1469, 1983.
9. Rubenstein, J.L.R., Nicolas, J.F. and Jacob, F. L'ARN non sens (nsARN); un outil pour inactiver specifiquement l'expression d'un gene donne in vivo. C. R. Acad. Sc. Paris, Serie III 299: 271-274, 1984.
10. Rubenstein, J.L.R., Nicolas, J.F., and Jacob, F. Construction of a retrovirus capable of transducing and expressing genes in multipotential embryonic cells. Proc. Natl. Acad. Sci. USA. 81: 7137-7140, 1984.
11. Nicolas, J.F., Rubenstein, J.L.R., Bonnerot, C. and Jacob, F. Introduction of genes into embryonal carcinoma cells and preimplantation embryos by use of a defective recombinant retrovirus. Cold Spring Harbor Symposium, 50: 713-720, 1985.
12. Rubenstein, J.L.R. , Nicolas, J.F. and Jacob, F. Introduction of genes into preimplantation embryos by use of a defective recombinant retrovirus. Proc. Natl. Acad. Sci. USA. 83:366-368, 1986.
13. Sanes, J.R., Rubenstein, J.L.R. and Nicolas, J.F. Use of a recombinant retrovirus to study post-implantation cell lineage in mouse embryos. The EMBO Journal. 5 (12):3133-3142, 1986.
14. Tecott, L., Rubenstein, J.L.R., Valentino, K., Evans, C. and Eberwine, J. Expression of the proenkephalin gene during development of the Rat neostriatum. Developmental Brain Research, 49: 75-86, 1989.
15. Rubenstein, J.L.R., Brice, A.E.J., Ciaranello, R.D., Denney, D., Porteus, M.H. and Usdin, T.B. Subtractive hybridization system using single-stranded phagemids with directional inserts. Nucleic Acids Research. 18 (16): 4833-4842, 1990.
16. Porteus, M. H., Bulfone, A., Ciaranello, R.D. and Rubenstein, J.L.R. Isolation and Characterization of a Novel cDNA Encoding a Homeodomain That Is Developmentally Regulated in the Ventral Forebrain. Neuron, 7: 221-229, 1991.
17. Porteus, M.H., Brice, A.E.J., Bulfone, A., Usdin, T.B., Ciaranello, R.D. and Rubenstein, J.L.R. Isolation and characterization of a library of cDNA clones that are preferentially expressed in the embryonic telencephalon. Molecular Brain Research,12: 7-22, 1992.
18. Özcelick, T., Porteus, M. H., Rubenstein, J.L.R. and Francke, U. DLX2 (TES1), a homeobox gene of the Distal-less family, assigned to conserved regions on human and mouse chromosomes 2. Genomics, 13: 1157-1161, 1992.
19. Bulfone, A. Kim, H.-J., Puelles, L., Porteus, M.H., Grippo, J.F. and Rubenstein, J.L.R. The mouse Dlx-2 (Tes-1) gene is expressed in spatially restricted domains of the forebrain, face and limbs in midgestation mouse embryos. Mechanisms of Development. 40, 129-140, 1993.
20. Bulfone A., Puelles, L., Porteus, M.H., Frohman, M.A., Martin, G.R. and Rubenstein, J.L.R. Spatially restricted expression of Dlx-1, Dlx-2 (Tes-1), Gbx-2, and Wnt-3 in the embryonic day 12.5 mouse forebrain defines potential transverse and longitudinal segmental boundaries. J. Neuroscience. 13(7), 3155-3172, 1993.
21. Puelles, L. and Rubenstein, J.L.R. Expression patterns of homeobox and other putative regulatory genes in the embryonic mouse forebrain suggest a neuromeric organization. Trends in Neuroscience. 16(11), 472-479, 1993.
22. Rubenstein, J.L.R. and Puelles, L. Homeobox gene expression during development of the vertebrate brain. Current Topics in Developmental Biology. ed: R. Pederson. Academic Press, 29, 1-64, 1994.
23. Porteus MH, Bulfone A, Liu, JK, Puelles, L, Lo, LC and Rubenstein JLR (1994) DLX-2, MASH-1, MAP-2 expression and bromodeoxyuridine incorporation define molecularly distinct cell populations in the embryonic mouse forebrain. J. Neuroscience, 14, 6370-6383, 1994.
24. Rubenstein, J.L.R., Martinez, S., Shimamura, K. and Puelles, L. (1994) The prosomeric model: a proposal for the organization of the embryonic forebrain. Science. 266, 578-560. (peer reviewed review article).
25. Thomas, B.L., Porteus, M.H., Rubenstein, J.L.R. and Sharpe, P.T. (1995) The spatial localization of Dlx-2 during tooth development. Connective Tissue Research. 31, 1-8.
26. Compagnone, N.A., Bulfone, A., Rubenstein, J.L.R. and Mellon, S.H. (1995) Expression of the steroidogenic enzyme P450scc in the central and peripheral nervous systems during rodent embryogenesis. Endocrinology, 136, 2689-2696.
27. Compagnone, N.A., Bulfone, A., Rubenstein, J.L.R. and Mellon, S.H. (1995) Steroidogenic enzyme P450c17 is expressed in the embryonic central nervous system. Endocrinology, 136, 5212-5223.
28. Bulfone, A., Smiga, S.M., Shimamura, K., Puelles, L., Peterson, A. and Rubenstein, J.L.R. (1995) T-Brain (Tbr-1): A homologue of Brachyury whose expression defines molecularly distinct domains within the cerebral cortex. Neuron,15, 63-78.
29. Zhu, W., Dahmen, J., Bulfone, A., Rigolet, M., Hernandez, M.C., Kuo, W.L., Biggs, J., Puelles, L., Rubenstein, J.L.R. and Israel, M.A. (1995) Id gene expression during development and molecular cloning of the human Id-1 gene. Molecular Brain Research,30,312-326.
30. Qiu, M., Bulfone, A., Martinez, S., Meneses, J.J., Shimamura, K., Pedersen, R.A. and Rubenstein, J.L.R. (1995) Role of Dlx-2 in Head Development and Evolution: Null Mutation of Dlx-2 Results in Abnormal Morphogenesis of Proximal First and Second Branchial Arch Derivatives and Abnormal Differentiation in the Forebrain. Genes and Development, 9, 2523-2538.
31. Shimamura, K., Hartigan, D.J., Martinez, S., Puelles, L. and Rubenstein, J.L.R. (1995) Longitudinal organization of the anterior neural plate and neural tube. Development, 121, 3923-3933.
32. Hartigan, D.J. and Rubenstein, J.L.R. (1996). The cDNA sequence of murine Nkx-2.2. Gene. 168, 271-272.
33. Fan, C.M., Kuwana, E., Bulfone, A., Fletcher, C., Copeland, N.G., Jenkins, N.A., Crews, S., Martinez, S., Puelles, L., Rubenstein, J.L.R. and Tessier-Lavigne, M. (1996) Expression patterns of two murine homologs of Drosophila Single-Minded suggest possible roles in embryonic patterning and in the pathogenesis of Down syndrome. Molecular & Cellular Neuroscience 7:1-16.
34. McGuinness, T., Porteus, M. H., Smiga, S., Bulfone, A., Kingsley, C., Qiu, M., Liu, J.K., Long, J.E., Xu, D., and Rubenstein, J.L.R. (1996) Sequence, organization and transcription of the Dlx-1 and Dlx-2 locus. Genomics, 35, 473-485.
35. Qiu, M., Anderson, S., Chen, S., Meneses, J. J., Hevner, R., Kuwana, E., Pedersen, R. A., and Rubenstein, J.L.R. (1996) Mutation of the Emx-1 Homeobox gene disrupts the corpus callosum. Developmental Biology. 178, 174-178.
36. Shimamura, K. , Martinez, S., Puelles, L. and Rubenstein, J.L.R. (1997). Patterns of gene expression in the neural plate and neural tube subdivide the embryonic forebrain into transverse and longitudinal domains. Developmental Neuroscience, 19, 88-96.
37. Rubenstein, J.L.R. and K. Shimamura. Regulation of patterning and differentiation in the embryonic vertebrate forebrain. in: Molecular and Cellular Approaches to Neural Development. (1997) W.M. Cowan, T.M. Jessel, S.L. Zipursky, Eds., Oxford University Press, Oxford, Chapter 10, 356-390.
38. Ding, M., Robel, L., James, A.J., Eisenstat, D.D., Leckman, J.F., Rubenstein, J.L.R. and Vaccarino, F.M. The Dlx2 homeobox gene controls neuronal differentiation in primary cultures of developing basal ganglia. (1997) J. Molecular Neuroscience, 8, 93-113.
39. Hernandez, M.C., Andres-Barquin, P.J., Martinez, S., Bulfone, A., Rubenstein, J.L.R. and Israel, M.A. (1997). ENC-1: A novel mammalian Kelch-related gene specifically expressed in the nervous system encodes an actin-binding protein. J. Neuroscience, 17, 3038-3051.
40. Qiu, M.S., Bulfone, A., Ghattas, I., Meneses, J.J., Christensen, L., Sharpe, P.T., Presley, R., Pedersen, R.A., and Rubenstein, J.L.R. (1997). Role of Dlx-1 and Dlx-2 in proximodistal patterning of the branchial arches: mutations alter morphogenesis of proximal skeletal elements derived from the first and second arches. Developmental Biology, 185, 165-184.
41. Shimamura, K and Rubenstein, J.L.R. (1997) Inductive Interactions Direct Early Regionalization of the Mouse Forebrain. Development, 124, 2709-2718.
42. Anderson, S., Qiu, M., Bulfone, A., Eisenstat, D., Meneses, J.J., Pedersen, R.A., & Rubenstein, J.L.R. (1997). Mutations of the homeobox genes Dlx-1 and Dlx-2 disrupt the striatal subventricular zone and differentiation of late-born striatal cells. Neuron, 19, 27-37.
43. Wassarman, K.M., Lewandowski, M., Campbell, K., Joyner, A.L., Rubenstein, J.L.R., Martinez, S. and Martin, G.R. (1997). Specification of the anterior hindbrain and establishment of a normal mid/hindbrain organizer is dependent on Gbx2 gene function. Development, 124, 2923-2934.
44. Liu, J.K., Ghattas, I., Liu, S., Chen, S. and Rubenstein, J.L.R. (1997) The Dlx Genes Encode DNA-Binding Proteins That Are Expressed In An Overlapping And Sequential Pattern During Basal Ganglia Differentiation. Developmental Dynamics, 210, 498-512.
45. Thomas, B.L., Tucker, A.S., Qiu, M., Ferguson, C.A., Hardcastle Z, Rubenstein, J.L.R. & Sharpe, P.T. (1997) Role of Dlx-1 and Dlx-2 genes in patterning of the murine dentition. Development, 124, 4811-4818.
46. Anderson S.A., Eisenstat D., Shi L. and Rubenstein J.L.R. (1997) Interneuron
migration from basal forebrain:dependence on Dlx genes. Science, 278, 474-476.
47. Rubenstein, J.L.R., Shimamura, K., Martinez, S. and Puelles, L. (1998) Regionalization of the prosencephalic neural plate, Annual Reviews of Neuroscience, 21, 445-478
48. Sussel, L., J. Kalamaras, D.J. Hartigan, J. Meneses, R. Pederson, J.L.R.
Rubenstein and M.S.German, (1998). Mice lacking the homeobox transcription factor Nkx-2.2 have diabetes due to arrested differentiation of pancreatic beta cells. Development, 125, 2213-2221.
49. Qiu, M., Shimamura, K., Sussel, L., Chen, S. and Rubenstein, J.L.R. (1998) Control of anteroposterior and dorsoventral domains of Nkx-6.1 gene expression relative to other Nkx genes during vertebrate CNS development. Mech. of Develop. 72, 77-88.
50. Ye, W., Shimamura, K., Rubenstein, J.LR., Hynes, M. and Rosenthal, A. (1998) Intersections of the FGF8 and Shh signals create inductive centers for dopaminergic and serotonin neurons in the anterior neural plate. Cell, 93, 755-766.
51. Rubenstein, JLR and Beachy, PA. (1998) Patterning of the embryonic forebrain. Current Opinions in Neurobiology. 8, 18-26.
52. Thomas, B.L., Tucker, A.S., Ferguson, C.A., Qiu, M., Rubenstein, J.L.R. & Sharpe, P.T. (1998) Molecular control of odontogenic patterning:positional dependent initiation and morphogenesis. Eur. J. Oral Sci. 106,(suppl 1):44-47.
53. Lindral, A.C., Romitti, P.A., Basart, A.M., Doetschman, T., Leysens, N.J., Daack-Hirsch, S., Semina, E.V., Johnson, L.R., Machida, J., Burds, A.A., Parnell, T., Rubesntein, J.L.R. and Murray, J.C. (1998) Association of MSX1 and TGFB3 with nonsyndromic clefting in humans. Am. J. Hum. Genet. 63(2):557-568
54. Rubenstein, J.L.R. (1998). Development of serotonergic neurons and their projections. Biol. Psych. 44, 145-150.
55. Bulfone, A., Wang, F., Hevner, R., Anderson, S., Cutforth, T, Chen, S., Meneses, J., Pedersen, R., Axel, R. and Rubenstein, J.L.R. (1998). An olfactory sensory map develops in the absence of normal projection neurons or gabaergic interneurons. Neuron, 21, 1273-1282.
56. Rubenstein J.L.R. (1998). Development of the cerebral cortex: V. Transcription factors and brain development. Journal of the American Academy of Child and Adolescent Psychiatry, 37(5):561-2.
57. Rubenstein J.L.R. (1998). Images in neuroscience. Brain development I. The neural plate. American Journal of Psychiatry, 155(3):324.
58. Timpe, L.C., Jin, K.L., Puelles, L. and Rubenstein, J.L.R. (1999) Cyclic nucleotide-gated cation channel expression in chicken embryos. Molecular Brain Research, 66(1-2):175-178.
59. Golden, J.A., Bracilovic, A., McFadden, KA, Beesely, JS, Rubenstein, JLR, and Grinspan, JB (1999) Ectopic BMP5 and BMP4 in the chick forebrain leads to cyclopia and holoprosencephaly. Proc. Natl. Acad. Sci., 96, 2439-2444.
60. Briscoe, J., Sussel, L., Serup, P., Hartigan-O’Connor, D. Jessell, T., Rubenstein, J.L.R. and Ericson, J. (1999) The Nkx2.2 Homeobox Gene Mediates Graded Sonic Hedgehog Signaling and Controls Ventral Neuronal Subtype Identity. Nature, 398, 622-627.
61. Bulfone, A. , Martinez, S., Russ, A., Campanella, M., Basile, A. , Quaderi, N., Gattuso, C., Rubenstein, J.L.R. and Ballabio, A. (1999) Expression pattern of the Tbr-2 (Eomesodermin) during mouse and chick brain development. Mechanisms of Development, 84, 133-138.
62. Anderson, S., Mione, M., Yun, K. and Rubenstein, J.L.R. (1999) Differential origins of neocortical projection and local circuit neurons: role of Dlx genes in neocortical interneuronogenesis. Cerebral Cortex,9: 646-654.
63. Rubenstein, J.L.R., Anderson, S., Shi, L., Miyashita-Lin, E., Bulfone, A., and Hevner, R. (1999) Genetic Control of Cortical Regionalization and Connectivity. Cerebral Cortex, 9: 524-532.
64. Sussel, L., Marin, O., Kimura, S., Rubenstein, J.L.R. (1999) Loss of Nkx2.1 homeobox gene function results in a ventral to dorsal respecification within the basal telencephalon: evidence for a transformation of the pallidum into the striatum. Development, 126, 3359-3370.
65. Miyashita-Lin, E.M., Hevner, R., Montzka Wassarman, K., Martinez, S. and Rubenstein, J.L.R. (1999) Early Neocortical Regionalization Is Preserved in the Absence of Thalamic Innervation. Science, 285: 906-909.
66. Begbie J; Brunet JF; Rubenstein JL; Graham A. (1999) Induction of the epibranchial placodes. Development, 126(5):895-902.
67. Martinez S; Crossley PH; Cobos I; Rubenstein JL; Martin GR. (1999) FGF8 induces formation of an ectopic isthmic organizer and isthmocerebellar development via a repressive effect on Otx2 expression. Development,126(6):1189-2000
68. Marcus, R.C., Shimamura, K., Sretevan, D., Lai, E., Mason, C.A. and Rubenstein, J.L.R. (1999). Domains of regulatory gene expression and the developing optic chiasm: correspondence with retinal axon paths and candidate signalling cell. Journal of Comparative Neurology, 403:346-358.
69. Depew, M.J., Liu, J.K., Long, J.E., Presley, R., Meneses, J.J., Pedersen, R.A., and Rubenstein, J.L.R. (1999). Dlx5 regulates regional development of the branchial arches and sensory capsules. Development, 126, 3831-3846.
70. Eisenstat, D.D., Liu, J.K, Mione, M., Zhong, W., Yu, G., Anderson, S.A., Ghattas, I., Puelles, L. and Rubenstein, J.L.R. (1999). DLX-1, DLX-2 and DLX-5 Expression Define Distinct Stages of Basal Forebrain Differentiation. Journal of Comparative Neurology 414:217-237
71. Puelles, L., Kuwana, E., Puelles, E. and Rubenstein, J.L.R. (1999) Comparison of the mammalian and avian telencephalon from the perspective of gene expression data. European Journal of Morphology. 37, 139-150.
72. Trumpp, A., Depew, M.J., Rubenstein, J.L.R., Bishop, J.M. and Martin, G.R. (1999). Cre-mediated gene inactivation demonstrates that FGF8 is required for cell survival and patterning of the first branchial arch. Genes and Development, 13, 3136-3148.
73. Rubenstein, J.L.R. and Rakic, P. (1999). Genetic control of cortical development. Cerebral Cortex. 9: 521-523.
74. Galceran, J., Miyashita-Lin, E.M., Devaney, E., Rubenstein, J.L.R. and Grosschedl, R. (2000). Hippocampus development and generation of dentate gyrus granule cells is regulated by LEF-1. Development, 127, 469-482.
75. Zerucha, T.S., Stuhmer, T., Park, B.K., Long, Q., Yu, G., Hatch, G., Gambarotta, A., Schultz, J., Rubenstein, J.L.R. and Ekker, M. (2000) A highly conserved enhancer in the Dlx5/Dlx6 intergenic region is the site of cross-regulatory interactions between Dlx genes in the embryonic forebrain. J Neuroscience, 20, 709-721.
76. Thomas, B.L., Liu, J.K, Rubenstein, J.L.R. and Sharpe, P.T. (2000) Independent regulation of Dlx-2 expression in the epithelium and mesenchyme of the first branchial arch. Development 127, 217-224.
77. Puelles, L., Kuwana, E., Bulfone, A., Shimamura, K., Keleher, J., Smiga, S., Puelles, E., and Rubenstein, J.L.R. (2000) Pallial and subpallial derivatives in the embryonic chick and mouse telencephalon, traced by the expression of the Dlx-2, Emx-1, Nkx-2.1, Pax-6 and Tbr-1 genes. Journal of Compartive Neurology, 424, 409-438.
78. Marín, O., Anderson, S.A. and Rubenstein, J.L.R. (2000) Origin and molecular specification of striatal interneurons, J. Neuroscience, 20, 6063-6076.
79. Rubenstein, J.L.R. (2000) Intrinsic and Extrinsic Control of Cortical Development. Novartis Symposium 228: Evolutionary Developmental Biology of the Cerebral Cortex. Wiley, 67-74.
80. Parnavelas, J.G., Anderson, SA, Lavdas, AA, Grigoriou, M.. Pachnis V. and Rubenstein, J.L.R. (2000). The contribution of the ganglionic eminence to the neuronal cell types of the cerebral cortex. Novartis Symposium 228: Evolutionary Developmental Biology of the Cerebral Cortex. Wiley, 129-138.
81. Sander, M., Paydar, S., Ericson, J., Briscoe, J., Berber, E. German, M., Jessell., T. and Rubenstein, J.L.R. (2000). Ventral neural patterning by Nkx homeobox genes: Nkx6.1 control somatic motor neuron and ventral interneuron fates. Genes and Development, 14, 2134-2139.
82. Pleasure, S.J., Anderson, S, Hevner, R., Bagri, A., Marin, O., Lowenstein, D.H., Rubenstein, J.L.R. (2000) Cell migration from the ganglionic eminences is required for the development of hippocampal GABAergic interneurons. Neuron. 28, 727-740.
83. Wilson, S. W. and Rubenstein, J.L.R. (2000) Induction and dorsoventral patterning of the telencephalon. Neuron 28, 641-651.
84. Yun, K, Potter, S and Rubenstein, J.L.R. (2001) Gsh2 and Pax6 play complementary roles in dorsoventral patterning of the mammalian telencephalon. Development 128, 193-205.
85. Anderson SA, Marín O, Horn C, Jennings K, Rubenstein JL. Distinct cortical migrations from the medial and lateral ganglionic eminences. Development. 2001 Feb;128(3):353-63.
86. Hevner, R.F., Shi, L., Justice, N., Hsueh Y-P, Sheng, M., Smiga, S., Bulfone, A., Goffinet, A.M. and Rubenstein, J.L.R. (2001) Tbr1 regulates differentiation of the preplate and layer 6. Neuron, 29. 353-366.
87. Puelles, E., Rubenstein, JLR, Puelles, L. (2001). Chicken Nkx6.1 expression at advanced stages of development identifies distinct brain nuclei derived from the basal plate. Mech. of Develop. 102, 279-282.
88. Kim, A.S, Anderson, S.A., Rubenstein, JLR,. Lowenstein, DK, and Pleasure, SJ (2001). Pax-6 regulates developmental expression of SFRP-2 and Wnt-7b in the developing central nervous system. J. Neurosci. 21, RC132.
89. Marin, O. and Rubenstein, J.L.R. (2002) Patterning, regionalization and cell differentiation in the forebrain. In: Mouse Development, Editors: J. Rossant and P. Tam. Academic Press. 75-106.
90. Schneider, R. Hu, D. Rubenstein, J.L.R., Maden, M. and Helms J.A. (2001) Local Synthesis of retinoids coordinates forebrain and facial morphogenesis by maintaining FGF and SHH. Development. 128:2755-2767.
91. Qi, Y., Cai, J., Wu, Y., Lee, J., Wu, R., Sussel, L., Rao, M., Rubenstein, J.L.R. and Qiu, M. (2001) Control of oligodendrocyte differentiation by the Nkx-2.2 homeodomain transcription factor. Development. 128: 2723-2733.
92. Selleri, L., Depew, M.J, Jacobs, Y., Chanda, S.K., Cheah, K., Rubenstein, J.L.R., O’Gorman, S., and Cleary, M. (2001). Requirement for Pbx1 in Patterning of the Skeleton and Programming of Chondrocyte Maturation, Development, 128:3543-3557.
93. Pham, TA, Rubenstein, JLR, Alcino J. Silva, AJ, Storm, D, and Stryker, M. (2001). The CRE/CREB Transcriptional Pathway Is Transiently Expressed during Thalamic Circuit Development and Is Required for Accurate Refinement of Retinogeniculate Axons. Neuron, 31:409-420.
94. Crossley, P.H., Martinez, S., Ohkubo, Y. and Rubenstein, J.L.R. (2001). Evidence That Coordinate Expression of Fgf8, Otx2, Bmp4, and Shh in the Rostral Prosencephalon Define Patterning Centers for the Telencephalic and Optic Vesicles. Neuroscience, 108(2):183-206
95. Marín O, Yaron A, Bagri A, Tessier-Lavigne M, Rubenstein JL. Sorting of striatal and cortical interneurons regulated by semaphorin-neuropilin interactions. Science. 2001 Aug 3;293(5531):872-5.
96. Xu, C., Harris, M.A., Rubenstein, J.L.R., Mundy, G.R. and Harris, S.E. (2001) Bone Morphogenetc Protein-2 (BMP-2) Signaling to the Col2a1 gene in chondroblasts requires the homeobox gene Dlx-2. DNA and CELL BIOL. 20, 359-365.
97. Yu, G., Zerucha, T., Ekker, M., Rubenstein, J.L.R. (2001) A PDZ-domain protein that is expressed in the embryonic forebrain co-activates transcription with DLX homeodomain proteins. Developmental Brain Research, 130, 217-230.
98. Marin, O. and Rubenstein, J.L.R. (2001) A Long, Remarkable Journey: Cellular and Molecular Mechanisms of Tangential Migration in the Telencephalon. Nature Neuroscience Reviews, 2, 780-790.
99. Cobos-Sillero, I., Shimamura, K., Rubenstein, J.L.R. and Martinez, S., Puelles, L., (2001). Fate map of the avian forebrain at stage 8 with quail-chick chimeras. Developmental Biology, 239, 46-67.
100. Stühmer, T., Puelles, L., Ekker, M and Rubenstein, J.L.R. (2002). Expression From A Dlx Gene Enhancer Marks Adult Mouse Cortical GABAergic Neurons. Cerebral Cortex 12:75-85.
101. Ohkubo, Y., Chiang, C. and Rubenstein, J.L.R (2002) Coordinate regulation and synergistic actions of BMP4, SHH and FGF8 in the rostral prosencephalon regulate morphogenesis of the telencephalic and optic vesicles. Neuroscience, 111, 1-17.
102. Stühmer, T., Anderson, S.A., Ekker, M and Rubenstein, J.L.R. (2002) Ectopic Expression of the Dlx genes induces Glutamic Acid Decarboxylase and Dlx expression. Development, 129: 245-252
103. Marín O, Baker J, Puelles L and Rubenstein JLR (2002) Patterning of the basal telencephalon and hypothalamus is essential for guidance of cortical projections. Development 2002 129: 761-773.
104. Bagri, A., Marin, O., Plump, A.S., Mak, J., Pleasure, S.J., Rubenstein, J.L.R. and Tessier-Lavigne, M. (2002) Slit proteins prevent midline crossing and determine dorsoventral position of major axonal pathways in the mammalian forebrain. Neuron, 33: 233-248.
105. Garda, A.L., Puelles, L., Rubenstein, J.L.R. and Medina, L. (2002) Expression patterns of Wnt8b and Wnt7b in the chicken embryonic brain suggest a correlation with forebrain patterning centers and morphogenesis. Neuroscience, 113(3):689-698.
106. Hevner, R.F., Miyashita, E. and Rubenstein, J.L.R. (2002) Cortical and thalamic axon pathfinding defects in Tbr1, Gbx2, and Pax6 mutant mice: evidence that cortical and thalamic axons interact and guide each other. Journal of Comparative Neurology, 447(1):8-17.
107. Anderson, SA, Kaznowski, CS, Horn, C, Rubenstein, JLR and McConnell, S. (2002) Distinct origins of neocortical projection neurons and interneurons in vivo. Cerebral Cortex, 12(7):702-709.
108. Gorski. J.A., Talley, T., Qiu, M., Puelles, L, Rubenstein, JLR, and Jones, KR. (2002) Cortical excitatory neurons and glia, but not GABAergic neurons, are produced in the Emx1-expressing lineage. J. Neuroscience, 22(15):6309-6314.
109. Bishop, KM, Rubenstein, JLR, and O’Leary, DMO. (2002) Distinct actions of Emx1, Emx2 and Pax6 in regulating the specification of areas in the developing neocortex. J. Neuroscience, 22, 7627-7638.
110. Panganiban, G. and Rubenstein, JLR. (2002) Developmental functions of the Distal-less (Dlx) homeobox genes (Review). Development 129, 4371-4386.
111. Yun, K., Fischman, S., Johnson, J., Hrabe de Angelis, M., Weinmaster, G., and Rubenstein, J.L.R. (2002) Modulation Of The Notch Signaling By Mash1and Dlx1/2 Regulates Sequential Specification And Differentiation Of Progenitor Cell Types In The Subcortical Telencephalon. Development, 129, 5029-5040.
112. Depew, MJ, Lufkin, T. and Rubenstein, JLR, (2002) Specification of Jaw Subdivisions by Dlx Genes, Science, 298:381-385.
113. Faedo A, Ficara F, Ghiani M, Aiuti A, Rubenstein JL, Bulfone A. (2002) Developmental expression of the T-box transcription factor T-bet/Tbx21 during mouse embryogenesis. Mech Dev. 116(1-2):157-160.
114. Garel S, Yun K, Grosschedl R, Rubenstein JL. The early topography of thalamocortical projections is shifted in Ebf1 and Dlx1/2 mutant mice. Development. 2002 Dec;129(24):5621-34.
115. Bishop, KM, Garel, S, Nakagawa, Y, Rubenstein, JLR, and O’Leary, DMO. (2003) Emx1 and Emx2 regulate cortical size, lamination, neuronal differentiation and axonal connections. J. Comp. Neurol. 457:345-360.
116. Long, JE, Sonia Garel, S., Depew, M., Tobet, S., and Rubenstein, JLR, (2003) DLX5 Regulates Development of Peripheral and Central Components of the Olfactory System, J. Neuroscience, 23, 568-578.
117. Tran PV, Lee, MB, Marin, O. Xu, B., Riechardt, LF., Rubenstein, JLR and Ingraham, HA. (2003) Requirement of the orphan nuclear receptor SF-1 in terminal differentiation of ventral medial hypothalamic neurons. Molecular and Cellular Neuroscience. 22:441-453.
118. Storm, E., Rubenstein, JLR, and Martin, GR. (2003). Dosage of Fgf8 determines whether cell survival is positively or negatively regulated in the developing forebrain. Proc. Natl. Acad. Sci. 100, 1757-1762.
119. Garel, S, Huffman, KJ, and Rubenstein, JLR. (2003). A caudal shift in neocortical patterning in a Fgf8 hypomorphic mouse mutant. Development. 130, 1903-1914.
120. Marín O, and Rubenstein JLR, Cell Migration in the Forebrain. (2003). Annual Reviews of Neuroscience. 26:441-83
121. Andrews, G, Yun, K, Rubenstein, JLR and Mastick, GS. (2003) Dlx transcription factors specify dopaminergic neurons of the ventral thalamus. Molecular Cellular Neuroscience, 23, 107-121.
122. Yun, K, Garel, S, Fischman, S, and Rubenstein, JLR. (2003). Patterning of the Lateral Ganglionic Eminence by the Gsh1 and Gsh2 Homeobox Genes Is Required For Histogenesis of the Striatum and Olfactory Bulb and the Growth of Axons Through the Basal Ganglia. Journal of Comparative Neurology. 461(2):151-65.
123. Marín O, Plump AS, Flames N, Sánchez-Camacho C, Tessier-Lavigne M, Rubenstein JL. Directional guidance of interneuron migration to the cerebral cortex relies on subcortical Slit1/2-independent repulsion and cortical attraction. Development. 2003 May;130(9):1889-901.
124. Ghanem N, Jarinova O, Amores A, Long Q, Hatch G, Park BK, Rubenstein, JLR, and Ekker M (2003) Regulatory roles of conserved intergenic domains in vertebrate Dlx bigene clusters. Genome Research. 13:533-543.
125. Hevner RF, Daza, RAM, Rubenstein, JLR, Stunnenbeg H, Olavarria, JF, and Englund C. Beyond laminar fate: toward a molecular classification of cortical projection/pyramidal neurons. Developmental Neuroscience, 25: 139-51.
126. Blackshear, P.J, Graves, JP, Stumpo, DJ, Cobos, I., Rubenstein, JLR, and Zeldin, DC. (2003) Graded phenotypic response to partial and complete deficiency of a brain-specific transcript variant of the winged helix transcription factor RFX4, Development, 130(19):4539-4552.
127. Zhao, Y, Marín, O, Hermesz, E, Powell, A, Palkovits, M, Rubenstein, JLR and Westphal, H. (2003). The LIM-homeobox gene Lhx8 is required for the development of many cholinergic neurons in the mouse forebrain. Proc. Natl. Acad. Sci. USA. 100(15):9005-10.
128. Rubenstein, JLR and Merzenich, MM. (2003) Model of Autism: Increased Ratio of Excitation/Inhibition In Key Neural Systems. Genes, Brain and Behavior, 2:255-267.
129. Puelles, L and Rubenstein, JLR. (2003) Forebrain gene expression domains and the evolving prosomeric model. TINS. 26, 469-476.
130. Xu, Cobos, I, Rubenstein, JLR, and Anderson, SA. (2004) Origins of cortical interneuron subtypes. J. Neuroscience, 24:2612-2622.
131. Jones, EG and Rubenstein, JLR. (2004) Expression of regulatory genes during differentiation of thalamic nuclei in mouse and monkey. J. Comp. Neurol. 477:55-80.
132. Garel S, Rubenstein JLR. (2004) Intermediate targets in the formation of topographic projections: inputs from the thalamocortical system, TINS 27(9):533-9.
133. Medina, L, Legaz I, González G, de Castro F, Rubenstein JLR, and Puelles L. (2004) Dbx1, Neurogenin 2, Semaphorin 5A, Cadherin 8 and Emx1 distinguish ventral and lateral pallial histogenetic divisions in the developing mouse claustroamygdaloid complex. J. Comp. Neurol. 474:504–523.
134. Zarbalis K, May SR, Shen Y, Ekker M, Rubenstein JL, Peterson AS. A focused and efficient genetic screening strategy in the mouse: identification of mutations that disrupt cortical development. PLoS Biol. 2004 Aug;2(8):E219.
135. Pan Q, Li C, Xiao J, Kimura S, Rubenstein J, Puelles L, Minoo P. (2004) In vivo characterization of the Nkx2.1 promoter/enhancer elements in transgenic mice. Gene. 331:73-82.
136. Huffman, K, Garel, S, and Rubenstein, JLR (2004) Fgf8 Regulates The Development of Intra-Neocortical Projections, J. Neuroscience, 24(41):8917-8923.
137. Yun, K, Mantani, A, Watson N, Garel S, Rubenstein JLR and Israel M. (2004) HLH gene, Id4, regulates cortical progenitor proliferation and differentiation, Development, 131 (21), 5441-5448.
138. Wang, TF, Ding, NC, Wang, GS, Luo, SC, Lin, YL, Ruan Y, Hevner R, Rubenstein JLR, Hsueh YP, (2004) Identification of Tbr-1/CASK complex target genes in neurons, J. Neurochemistry. 91(6):1483-92.
139. Flames, N, Long, J, Garratt, T, Fischer, T, Gassmann, M, Birchmeier, C, Lai, C, Rubenstein, JLR and Marín, O. (2004) Short- and long-range attraction of cortical GABAergic interneurons by Neuregulin1. Neuron. 44, 251-261.
140. Faedo A, Quinn JC, Stoney P, Long JE, Dye C, Zollo M, Rubenstein JL, Price DJ, Bulfone A (2004) Identification and characterization of a novel transcript down-regulated in Dlx1/Dlx2 and up-regulated in Pax6 mutant telencephalon. Developmental Dynamics 231:614-620.
141. de Melo J, Du G, Fonseca M, Gillespie LA, Turk WJ, Rubenstein JLR and Eisenstat DD (2005) Dlx1 and Dlx2 function is necessary for terminal differentiation and survival of late-born retinal ganglion cells in the developing mouse retina. Development 132 311-322.
142. Cobos I, Broccoli V, and Rubenstein JLR. (2005) The vertebrate ortholog of Aristaless is regulated by Dlx genes in the developing forebrain. J Comp Neurol. 483(3):292-303.
143. Givens ML, Rave-Harel N, Goonewardena VD, Kurotani R, Berdy SE, Swan CH, Rubenstein JLR, Robert B, and Mellon PL. (2005) Developmental Regulation Of Gonadotropin Releasing Hormone Gene Expression By The Msx And Dlx Homeodomain Protein Families. JBC, 280(19): 19156-65.
144. Studer M, Filosa A, Rubenstein, JLR (2005) The nuclear receptor COUP-TFI represses differentiation of Cajal-Retzius cells. Brain Research Bulletin. 66(4-6):394-401.
145. Bulfone, A,, Carotenuto, P, Faedo, A, Aglio, V, Garzia, L, Bello, AM, Basile, A, Andre, A, Cocchia, M, Guardiola, O, Ballabio, A, Rubenstein, JLR and Zollo, M. Telencephalic embryonic subtractive sequences: a unique collection of neurodevelopmental genes. J. Neuroscience. (2005) 25(33):7586-600.
146. Kohwi M, Osumi N, Rubenstein JL, Alvarez-Buylla A. (2005). Pax6 is required for making specific subpopulations of granule and periglomerular neurons in the olfactory bulb. J Neurosci. 25(30):6997-7003.
147. Cobos I., Calcagnotto, ME, Vilaythong, AJ, Noebels, J, Baraban SC, Rubenstein JLR. (2005). Mice Lacking the Dlx1 Transcription Factor Exhibit Subtype-Specific Loss of Interneurons, Reduced Synaptic Inhibition and Epilepsy. Nature Neuroscience. 8:1059-1068.
148. Depew M, Simpson CA, Morasso M, and Rubenstein JLR (2005). Reassessing the Dlx Code: The Genetic Regulation of Branchial Arch Skeletal Pattern and Development. J. Anatomy. 207(5):501-561.
149. Sur, M, and Rubenstein, JLR. Patterning and plasticity of the cerebral cortex. Science, 310(5749):805-810. (peer reviewed review article)
150. Hamilton SP, Woo JM, Carlson EJ, Ghanem N, Ekker M, and Rubenstein JLR. (2005) Analysis of four DLX homeobox genes in autistic probands. BMC Genetics 2005, 6:52.
151. Sawamoto K, Wichterle H, Gonzalez-Perez O, Cholfin JA, Yamada M, Spassky N, Murcia NS, Garcia-Verdugo JS, Marin O, Rubenstein JLR, Tessier-Lavigne M, Okano H and Alvarez-Buylla A. (2006) Subventricular Neuroblasts Follow the Flow of Cerebrospinal Fluid in the Adult Brain. Science. 311:629-632.
152. Storm E, Garel S, Borello U, Hebert JM, Martinez S, McConnell S, Martin G and Rubenstein J. (2006) Dose-dependent functions of Fgf8 in regulating telencephalic patterning centers. Development. 133(9):1831-1844.
153. Cobos, I, Long J, Thwin M, Rubenstein JLR, (2006) Cellular Patterns of Transcription Factor Expression in Developing Cortical Interneurons. Cerebral Cortex, Suppl 1:82-88.
154. Polley D, Cobos I, Merzenich M and Rubenstein JLR. (2006) Dlx1 Mutant Mice Have Reduced Hearing. Hearing Research, 214(1-2):84-88.
155. Alvarez-Dolado M, Calcagnotto ME, Rubenstein JLR, Arturo Alvarez-Buylla A and Baraban SC (2006) Cortical inhibition modified by embryonic neural precursors grafted into the postnatal brain. J. Neuroscience. 26(28):7380-7389.
156. Zhou, C, Borello, U, Rubenstein, JLR, Pleasure, S. (2006) Neuronal production and precursor proliferation defects in the neocortex of mice with loss of function in the canonical Wnt signaling pathway. Neuroscience, 142(4):1119-1131.
157. Monory K, Massa F, Egertova M, Eder M, Blaudzun H, Westenbroek R, Kelsch W, Jacob W, Marsch R, Ekker M, Long J, Rubenstein JL, Goebbels S, Nave KA, During M, Klugmann M, Wolfel B, Dodt HU, Zieglgansberger W, Wotjak CT, Mackie K, Elphick MR, Marsicano G, Lutz B. (2006). The endocannabinoid system controls key epileptogenic circuits in the hippocampus. Neuron. 51(4):455-466.
158. Long, JE, Garel, S, Dolado M, Yoshikawa K, Osumi N, Zhou Q-Y, Alvarez-Buylla A, Rubenstein JLR. (2007). Dlx-Dependent and Independent Regulation of Olfactory Bulb Interneuron Differentiation, J. Neuroscience, 27(12):3230-3243.
159. Colombo, E., Collombat, P., Colasante, G., Bianchi, M., Long J., Mansouri A., Rubenstein, J.L.R., Broccoli, V. (2007) Inactivation of Arx, the murine ortholog of the XLAG gene, leads to severe disorganization of the ventral telencephalon with impaired neuronal migration and differentiation. J. Neuroscience, 27(17):4786-4798.
160. Cholfin J and Rubenstein JLR (2007) Patterning of frontal cortex subdivisions by Fgf17. PNAS. 1;104(18):7652-7657.
161. Cobos I, Borello U, Rubenstein JLR. (2007) Dlx transcription factors promote migration through repression of axon and dendrite growth. Neuron. 54, 873–888.
162. Kohwi M, Petryniak MA, Long JE, Ekker M, Obata K, Yanagawa Y, Rubenstein JL, Alvarez-Buylla A. A subpopulation of olfactory bulb GABAergic interneurons is derived from Emx1- and Dlx5/6-expressing progenitors. J Neurosci. 2007 Jun 27;27(26):6878-91.
163. Ghanem N, Yu M, Long J, Hatch G, Rubenstein JL, Ekker M. (2007) Distinct cis-regulatory elements from the Dlx1/Dlx2 locus mark different progenitor cell populations in the ganglionic eminences and different subtypes of adult cortical interneurons. J Neurosci. 27(19):5012-22.
164. Flames N, Gelman DM, Pla R, Rubenstein JLR, Puelles L & Marín O. (2007) Delineation of multiple subpallial progenitor domains by the combinatorial expression of transcriptional codes. J. Neuroscience 27(36):9682-95.
165. Petryniak MA, Potter GB, Rowitch DH, Rubenstein JL. (2007) Dlx1 and Dlx2 Control Neuronal versus Oligodendroglial Cell Fate Acquisition in the Developing Forebrain. Neuron. 55(3):417-433.
166. García-López, M; Abellán, A; Legaz, I; Rubenstein, J; Puelles, L; Medina, L. (2008) Histogenetic compartments of the mouse centromedial and extended amygdala based on gene expression patterns during development. J Comp Neurol. 506(1):46-74
167. Scearce-Levie K, Roberson ED, Gerstein H, Cholfin JA, Mandiyan VS, Shah NM, Rubenstein JL, Mucke L. (2007). Abnormal social behaviors in mice lacking Fgf17. Genes Brain Behav. 2007 Oct 1; [Epub ahead of print]. PMID: 17908176.
168. Cholfin JA and Rubenstein JL. (2008) Frontal cortex subdivision patterning is coordinately regulated by Fgf8, Fgf17 and Emx2. J. Comp. Neurol., 509(2):144-55.
169. Li, G, Adesnik H, Li J, Long J, Nicoll R, Rubenstein JLR, Pleasure SJ (2008) Regional distribution of cortical interneurons and development of inhibitory tone is regulated by Cxcl12/Cxcr4 signaling. J. Neuroscience.28(5):1085-98.
170. Zhao, Y., Flandin-Blety, P., Long, J.E., dela Cuesta, M., Westphal, H., Rubenstein, J.L. (2008). Distinct Molecular Pathways for Development of Telencephalic Interneuron Subtypes Revealed Through Analysis of Lhx6 Mutants, J. Comp. Neurol. 510:79 –99.
171. Lu A, Steiner MA, Whittle N, Vogl A, Walser SM, Ableitner M, Refojo D, Ekker M, Rubenstein JL, Stalla G, Singewald N, Holsboer F, Wotjak CT, Wurst W, Deussing JM. (2008) Conditional mouse mutants highlight mechanisms of corticotropin-releasing hormone effects on stress coping behavior. Molecular Psychiatry, in press 2008.
172. Bardet SM, Martinez-de-la-Torre M, Northcutt RG, Rubenstein JL, Puelles L. Conserved pattern of OTP-positive cells in the paraventricular nucleus and other hypothalamic sites of tetrapods. Brain Res Bull. 2008 Mar 18;75(2-4):231-5
173. Faedo A, Tomassy GS, Ruan Y, Teichmann H, Krauss S, Pleasure SJ, Tsai SY, Tsai MJ, Studer M, Rubenstein JL. COUP-TFI Coordinates Cortical Patterning, Neurogenesis, and Laminar Fate and Modulates MAPK/ERK, AKT, and {beta}-Catenin Signaling. Cereb Cortex. 2007 Dec 28; [Epub ahead of print].
174. Vasudevan A, Long JE, Crandall JE, Rubenstein JL, Bhide PG. Compartment-specific transcription factors orchestrate angiogenesis gradients in the embryonic brain. Nat Neurosci. 2008 Apr;11(4):429-39.
175. Jeong J, Li X, McEvilly R, Rosenfeld M, Lufkin T, and Rubenstein J. (2008). Dlx genes pattern mammalian jaw primordium by regulating both lower jaw- and upper jaw-specific genetic programs. Development. 135, 2905-2916.
176. Ghanem N, Yu M, Poitras L, Rubenstein JLR, Ekker M. Characterization of a distinct subpopulation of striatal projection neurons expressing the Dlx genes in the basal ganglia through the activity of the I56ii enhancer. Dev. Biol. In press.
177. Borello U, Cobos I, Long JE, Murre C, and Rubenstein JLR, FGF15 promotes neurogenesis and opposes FGF8 function during neocortical development. Neural Development. 2008 Jul 14;3:17.
178. Long JE, Swan C, Liang WS, Cobos I. Potter GB and Rubenstein JLR, Dlx1&2 and Mash1 Transcription Factors Control Striatal Patterning and Differentiation Through Parallel and Overlapping Pathways. J. Comp. Neurol. In press.
179. Sunwoo JB, Kim S, Yang L, Naik T, Higuchi DA, Rubenstein JL, Yokoyama WM. Distal-less homeobox transcription factors regulate development and maturation of natural killer cells. Proc Natl Acad Sci U S A. 2008 Aug 5;105(31):10877-82.
180. Ohtsuka N, Tansky MF, Kuang H, Kourrich S, Thomas MJ, Rubenstein JL, Ekker M, Leeman SE, Tsien JZ. Functional disturbances in the striatum by region-specific ablation of NMDA receptors. Proc Natl Acad Sci U S A. 2008 Aug 26. [Epub ahead of print]
Clinical Articles
1. Rubenstein, J.L.R., Steiner, H., Pratt, J. M. and Koran, L. M. Anorexia nervosa with bipolar disorder: a case report. Int. J. Eating Disorders. 9:221-225, 1991.
2. Rubenstein, J.L.R., Steiner, H., and Walton, C. Depression, episodic behavioral discontrol, and polydipsia following right temporal lobe damage. J. Amer. Acad. Child and Adolesc. Psychiatry. 29: 472-474, 1990.
3. Rubenstein, J.L.R., Johnston, K., Elliott, G.R. and Brusilow, S.W. Haloperidol-induced hyperammonaemia in a child with citrullinaemia. J. of Inherited Metabolic Disease, 13:754-755, 1990.
Non-Refereed Reviews
1. Nicolas, J.F., and Rubenstein, J.L.R. Retroviral Vectors. In: Vectors: a Survey of Molecular Cloning Vectors and Their Uses. Rodriguez, R. and Denhardt, D.T. (eds) Butterworth, 1988. (book chapter)
2. Rubenstein, J.L.R., Lotspeich, L. and Ciaranello, R.D. The neurobiology of developmental disorders. from: Advances in Clinical Child Psychology, vol 13, ed: B.B. Lahey and A.E. Kazdin. Plenum Press. 1-52, 1990. (book chapter)
3. Ciaranello, R.D., Wong, D.L. and Rubenstein, J.L.R. Molecular neurobiology and disorders of brain development. from: Application of Basic Neuroscience to Child Psychiatry. ed: S.I. Deutsch, A. Weizman, and R. Weizman. Plenum Press. 9-32, 1990. (book chapter)
4. Rubenstein, J.L.R. Gene Cloning. from: Molecular Medicine. ed: E. Rubenstein. Scientific American Medicine. 103-132, 1994. Note: This book won the 1995 British Medical Association Medical Book of the Year Award and First Prize for the Best Basic and Clinical Sciences Book.
5. Rubenstein, J.L.R. and Puelles, L. (1994) Homeobox gene expression during development of the vertebrate brain. Current Topics in Developmental Biology. ed. R. Pederson. Academic Press. 29, 1-64 .
6. Rubenstein, J.L.R. (1998). Development of serotonergic neurons and their projections. Biol. Psych. 44, 145-150.
7. Rubenstein, J.L.R. (1998). Images in Neuroscience. Brain development I. The neural plate. American Journal of Psychiatry, 155(3):324.
8. Rubenstein J.L.R. (1998) Development of the cerebral cortex: V. Transcription factors and brain development. Journal of the American Academy of Child and Adolescent Psychiatry, 37(5):561-562.
9. Rubenstein, J.L.R. (1999) Overview of brain development. In: The Neurobiology of Mental Illness. D. Charney, E.J. Nestler, B.S. Bunney, Eds. Oxford University Press. New York, New York, Chapter 1.
10. Rubenstein, J.L.R. and Rakic, P. (1999). Genetic control of cortical development. Cerebral Cortex. 9: 521-523.
11. Parnavelas, J.G., Anderson, SA, Lavdas, AA, Grigoriou, M.. Pachnis V. and Rubenstein, J.L.R. (2000). The contribution of the ganglionic eminence to the neuronal cell types of the cerebral cortex. Novartis Symposium 228: Evolutionary Developmental Biology of the Cerebral Cortex. Wiley, 129-138.
12. Rubenstein, J.L.R. (2000) Intrinsic and Extrinsic Control of Cortical Development. Novartis Symposium 228 on Evolutionary developmental biology of the cerebral cortex.67-82.
13. Puelles, L. and Rubenstein, J.L.R. (2002) Forebrain. Encyclopedia of the human brain. Academic Press. Vol. 2, 299-315.
14. Marin, O. and Rubenstein, J.L.R. (2002). Patterning, regionalization and cell differentiation in the forebrain. In: Mouse Development, Editors: J. Rossant and P. Tam. Academic Press. 75-106.
15. Rubenstein, JLR and Puelles, L. (2003) Development of the Nervous System. Molecular Basis Of Inborn Errors of Development. Epstein CJ, Erikson RP and Wynshaw-Boris A, editors. Oxford University Press. Chapter 8.
16. Garel, S. and Rubenstein, JLR. (2004) Patterning of the Cerebral Cortex. The Cognitive Neurosciences, 3rd edition. Michael S. Gazzaniga Editor-in-Chief. MIT Press. 69-84.
17. Puelles, L, Martínez S, Martinez de la Torre, M, and Rubenstein JLR (2004). Gene maps and related histogenetic domains in the forebrain and midbrain. Chapter 1, The Rat Nervous System. Third Edition. Ed. Paxinos, Elsevier-Academic Press. pp. 3-25.
18. Rubenstein, JLR and Puelles, L. (2004) Survey of Brain Development. Handbook of Mental Health Interventions in Children and Adolescents. Steiner, H, editor. Jossey-Bass Press. Chapter 5.
19. Belmonte, MK, EH Cook, GM Anderson, JLR Rubenstein, WT Greenough, A Beckel-Mitchener, E Courchesne, LM Boulanger, SB Powell, PR Levitt, EK Perry, Y Jiang, TM DeLorey, E Tierney. (2003). Autism as a Disorder of Neural Information Processing: Directions for Research and Targets for Therapy. Molecular Psychiatry. 9(7):646-663.
20. Understanding Autism: From Basic Neuroscience to Treatment (Book). Edited by Steven O. Moldin, John L. R. Rubenstein. CRC Press, 2006.
21. Rubenstein, JLR. Comments on the Genetic Control of Forebrain Development. Clinical Neuroscience Research. Submitted 12/05.
22. Moldin, SO, Rubenstein, JLR, Hyman, SE. (2006). Autism Speaks to Neuroscience. Commentary in: J. Neuroscience. 26(26):6893-6
23. Cholfin JA, Rubenstein JL. Genetic regulation of prefrontal cortex development and function. Novartis Found Symp. 2007;288:165-73; discussion 173-7, 276-81.